It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. What does the plaquenil test consist of Chloroquine and sun exposure If you are taking Plaquenil to treat an inflammatory condition or malaria, you should be aware of the side effects that may occur to your eyes and vision. Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage. This isn't scientific, just my sense after 15+ years of Plaquenil. As for depression, I think Plaquenil is actually a mild cortical stimulant, so people usually feel peppier because of it. BUT your elevated ferritin may be indicating an underlying inflammatory process. I just read, and this was news to me, that ferritin is an "acute phase. So glad you posted this and I now know I'm not the only one having the crazy reaction to Plaquenil. I have RA and was put on Plaquenil 1 week ago and noticed the extreme moods swings, frustration turning to extreme rage, feeling crazy, then crying over my reactions. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Plaquenil depression Plaquenil hydroxychloroquine sulfate dose, indications., Immune & Autoimmune - Lupus plaquenil causing depression maybe? Is gastrointestinal problems common from plaquenil Now I don't know what is the reason. I asked my doctor if plaquenil can be it, as I too have read the side effects. He said it's really really rare and he doesn't think so. I have a few possible answers. maybe before, as I took plaquenil together with medrol, the medrol inhibited some bad effects of plaquenil. Does Plaquenil affect your temperament? - LUPUS UK. Plaquenil Side Effects Of Bipolar And Depression Depression.. Can Plaquenil cause Major Depression? - Treato. Balances out the steroids and im guessing, the Plaquenil, because I had weird issues before with Plaquenil and this time I don't. I know they can be addictive so im careful, and I respect them, I try to skip if I can, but between anxiety from pills helping me to live better, and addicted to nerve pills, I choose all the above and lead a calm life Paracentral depression OD, OS. Plaquenil Hydrochloroquine or Aralen Chloroquine • Annual screening after 5 years of use **Interesting, The Royal College of Ophthalmologists in Great Britain does NOT recommend routine screening for toxicity with antimalarial drug use. Plaquenil received an overall rating of 5 out of 10 stars from 4 reviews. See what others have said about Plaquenil, including the effectiveness, ease of use and side effects.