Chloroquine is now uncommonly used in favor of its derivative hydroxychloroquine. In the United States, hydroxychloroquine is most often used for its anti-inflammatory effects in rheumatology and dermatology. Chloroquine and g6pd Ocular testing for plaquenil Plaquenil retinal Jan 18, 2019 Hydroxychloroquine Plaquenil was originally used to treat malaria and is now used mostly to treat rheumatological and dermatological diseases. Its most frequent use now is for Rheumatoid Arthritis RA and Lupus and is often very effective in mitigating the joint and arthritic symptoms these diseases can cause. The visual side effects are very rare, and are usually reversible if caught quickly, which is why anyone taking it should have plaquenil toxicity testing done every six months by their eye doctor. The only person I know with permanent vision deficits as a rsult of plaquenil was a tiny lady, weighing about 100 lbs soaking wet. Plaquenil’s long half-life in the body can cause irreversible and progressive damage, Dr. Fung said. Similarly, one study reported that 16 women who’d taken hydroxychloroquine or chloroquine, or a combination of the agents, showed no improvement seven years after stopping drug therapy, and progression occurred in six of the cases. 2 While early toxicity may be asymtomatic, patients with more advanced stage of toxicity may complain of color vision changes or paracentral scotomas. Its toxic effects on the retina are seen in the macula. Plaquenil eye problems reversible Plaquenil Side Effects Common, Severe, Long Term -, Have you witnessed vision problems from Plaquenil? - Lupus. Plaquenil y la aspirina Aug 29, 2014 Plaquenil, hydroxychloroquine HCQ, is an anti-malarial medication that has been proven to be useful in the treatment of patients with rheumatoid arthritis RA, systemic lupus erythematosus SLE and other inflammatory and autoimmune diseases. The Risk of Retinal Toxicity with Plaquenil. Rx Side Effects New Plaquenil Guidelines and More - American.. Protecting your eyesight when taking Plaquenil Lupus.. Aug 30, 2011 Fundus changes on biomicroscopy, including bull's eye maculopathy, are indicative of fairly advanced hydroxychloroquine-induced retinal toxicity which is largely irreversible despite cessation of the medication. RARE side effects. If experienced, these tend to have a Severe expression. Abnormal Liver Function Tests. Acute Liver Failure. Acute Pustular Eruptions On Skin. Bronchospasm. Decreased Blood Platelets. Decreased White Blood Cells. Most cases of eye disease occur in people receiving more than 400 mg of Plaquenil or more than 250 mg of Aralen daily. Atabrine is not known to cause retinal damage. Recent evidence shows that there is no irreversible eye damage with Plaquenil in doses of 5 mg/kg 2.3 mg/lb per day.